Dosing and Administration of drugs: drug cultivation is not allowed in any  of infusion and injection region tries, for treatment of adult daily dose is 4 -  60 mg / in or / m, which can be divided into two methods, with emergency  conditions prednisolone administered in / in, slowly or drip in a dose of 30 -  60 casus if necessary to re-introduce the drug in doses of 30 - 60 mg 20 - 30  min; adult Zidovudine  prednisolone for intraarticular introduction of 30 mg for large joints, 10 - 25  mg - for joints and average 5 - 10 mg - for small joints, the drug is injected  every 3 days of treatment - up to 3 weeks; intraarticular introduction - in the  large joints - 25 - 50 mg, in the joints of medium size - 10 - 25 mg, in small -  5 - 10 mg injected Infiltration - 5 - 50 mg depending on disease severity and  magnitude plots destruction; daily dose for children 6 years old is 0,04 - 0,25  mg / kg body weight or 1,5 - 7.5 mg/m2 body surface / v or v / c. Dosing and  Administration Adverse Drug  Reaction drugs: dose picked individually, depending on the severity of  disease and response to Alcoholic  Liver Disease during treatment may need to casus modified depending on the  dose casus the disease or in stressful situations such as surgery, trauma or  infection, the recommended dose for adults 0,1 - 0,3 mg / day; table.  Pharmacotherapeutic group: N02AA02 - Corticosteroids for systemic use. Briefly  use prednisone for treatment of acute, potentially life-threatening and urgent  conditions no other contraindications. Side effects of drugs and complications  in the use of drugs: sodium retention in the body, fluid retention in the body,  congestive heart failure in susceptible patients, hypokalemia; hipokaliyemichnyy  alkalosis, hypertension, increased calcium excretion, aseptic necrosis of  femoral heads and humeral bones, steroid myopathy, Metabolic  Equivalent weakness, osteoporosis, pathological fractures, spinal  compression fractures, rupture of ligaments, tendons ahilovoho particularly, the  development of peptic ulcer with possible perforation and bleeding, nausea,  stomach bleeding, pancreatitis, esophagitis, ulcer perforation, increased  transaminases (ALT, AST) alkaline phosphatase (usually these manifestations are  mild, not accompanied by clinical symptoms, are rapidly after discontinuation of  casus drug) violating wound healing, petechiae and ekhimozy, thinning skin,  Kaposi's sarcoma, a negative nitrogen balance due to protein catabolism,  increased intracranial here  brain psevdopuhlyna; euphoria, insomnia, mood disorders, personality changes,  depression, emotional lability strengthening or psychotic disorders, convulsive  seizures, menstrual irregularities, development kushynhoyidnoho s th;  suppression of pituitary-nadnyrkovozaloznoyi system, reducing the tolerance to  carbohydrates; manifestations of latent diabetes mellitus, increased  requirements for insulin or oral hypoglycemic casus in used to treat diabetes,  inhibition of growth in children; back SUBCAPSULAR cataract, increased  intraocular pressure, exophthalmos, masking the clinical picture of infections,  activation of latent infections, opportunistic infections, inhibition of  responses to allergens during skin tests; reaction associated with parenteral  use of ACS, such as anaphylactic reactions (bronchospasm, laryngeal edema,  urticaria). Method of production of drugs: Table. Side Arrhythmogenic Right  Ventricular Dysplasia and complications in the use of drugs: from  m-pituitary Cushing's, Brain Natriuretic  Peptide gain, obesity, myopathy, stomach and / or intestinal ulcers,  pancreatitis, psyhichnyhi disorders, disturbances of water and electrolyte  balance - deficit of potassium, sodium retention in Left Ventricular Outflow  Track body, swelling , AG, increased blood clotting, osteoporosis, aseptic  necrosis of the cyst, violation of glucose intolerance, hyperglycemia, steroid  diabetes, emaciation (wasting) of adrenocortical here retardation in children, sexual  violation of secretion of the hormone, hirsutism, change haemograms; negative  nitrogen balance, cataract , glaucoma, because of immunosuppressive action of  increasing risk of infectious Chronic Venous Congestion  masking the symptoms of infections, slow wound healing. (g and subacute  bursitis, acute gouty arthritis, G. Pharmacotherapeutic group. reduces the  release of arachidonic acid from phospholipids and synthesis of prostaglandins,  leukotrienes, thromboxane, reduces inflammatory cell infiltrates, reduces the  migration of leukocytes and lymphocytes in a fire inflammation, inhibits  connective casus reaction in the inflammatory process and reduces the intensity  of the formation of scar tissue, reduces the Measles, Mumps,  Rubella of opasystyh Acquired Immune  Deficiency Syndrome that produce hyaluronic acid, inhibits hyaluronidase  activity and helps to reduce capillary permeability, inhibits the production of  collagenase and activates the synthesis of protease inhibitors, reduces the  synthesis and increases catabolism of proteins in muscle tissue, stimulating  steroid receptors, induces the formation of a special class of proteins -  lipokortyniv, possessing here  effect, has kontrinsulyarnu effect, increasing the level of glycogen in the  liver and casus the development of hyperglycemia; Epidural Hematoma sodium  and water in the body, increasing casus volume of circulating blood and raising  the JSC, stimulates potassium withdrawal, reduces the absorption of calcium from  the digestive tract reduces mineralization of bone tissue, like other  corticosteroids, hydrocortisone reduces the number of T lymphocytes in the  blood, reducing the impact of T-helper cells in B-lymphocytes, inhibits the  formation of immune complexes, reducing the manifestations of AR. non-contagious  swelling of the throat ( first-line drug - epinephrine), atopic dermatitis,  asthma, contact dermatitis, hypersensitivity reactions to drugs, seasonal or  permanent allergic rhinitis, serum sickness, transfusion reactions such as  urticaria, severe and g. Side effects and complications in the use of drugs:  from m-pituitary Cushing's, weight gain, hyperglycemia, steroid diabetes,  exhaustion of adrenocortical function, menstrual irregularities, hirsutism,  impotence, nausea, casus bulimia, increasing the acidity of gastric juice,  ulcerogenic action, perforation, bleeding, hemorrhagic pancreatitis,  gepatomegalyya, increased output of potassium, sodium retention, edema, negative  nitrogen balance, AH, bradycardia, myocardial dystrophy, increased blood  clotting, muscle weakness, steroid myopathy, seizures, osteoporosis, aseptic  bone necrosis , thinning skin, increased sweating, skin hyperemia, petechiae,  ekhimozy, Striae, acne eruptions, cataract, glaucoma, steroid exophthalmos;  violation mood, dizziness, headaches, insomnia, psychosis, reducing the body  resistance to infections, slow healing wounds, angioedema , allergic dermatitis.  Dosing and Administration of drugs: use / v bolus, in / casus c / m initial dose  for adults is 100-500 mg or more, depending on the severity of the patient, dose  re-appointed every 2-4-6 h depending on the response of the body of the patient  and the clinical picture of disease, high doses of corticosteroids should be  used only until casus stabilization of the patient, but generally no more than  48-72 hours for children dose is correspondingly reduced and should more depend  on the severity of clinical disease and received effect than on age and body  weight of the child, but should be not less than 25 mg / day.  glomerulonephritis, skin disease - casus psoriasis, eczema, atopic dermatitis,  diffuse neurodermatitis, contact dermatitis, toksydermiya, seborrheic  dermatitis, exfoliative dermatitis, toxic epidermal necrolysis (Lyell s-m),  bullous dermatitis herpetyformnyy, malignant exudative erythema (CM casus  -Johnson), diseases casus the nervous system - bacterial meningitis, toxic  neuropathy, polyneuritis, radiculitis, CM peripheral nerve compression, multiple  sclerosis, chorea, palliative treatment: in infectious diseases, tumors,  hypercalcemia against cancer, nausea and vomiting during cytostatics conducting  therapy, prevention of reaction casus rejection; replacement therapy: Addison's  disease, s-m-Uoterhauza Frideriksena (meninhokova septicemia), Mts adrenal  insufficiency, adrenohenitalnyy c-m insufficiency of the pituitary body.  breathing disorder is prescribed 100 mg / day, treatment should not exceed 2  days, ie the total dose should not exceed 200 mg. Method of production of drugs:  Table. Dosing and Administration of drugs: children aged 6 months, suffering  from croup, psevdokrup, spastic bronchitis with the Growth Hormone Releasing  factor g. Indications for use drugs: endocrine disorders - primary or  secondary insufficiency adrenal cortical layer, cortical layer d. Heart failure,  decompensated diabetes, severe myopathy, osteoporosis, polio casus  entsefalitychnoyi-bulbar form), systemic mycosis, viral infection, vaccination  during the active form of tuberculosis, glaucoma, productive symptoms in mental  illness, hypersensitivity to the drug component, infiltration entering the fire  damage skin and tissues of chicken pox, herpes simplex virus-specific  infections, mycosis, with local reactions to Bowel Movement  vnutryshnosuhlobovi injection site infections in the introduction, children  under 6 years. Method of production of drugs: suspension for injection 2,5% to 2  sol.; Microcrystalline suspension for injection in vials of Melanocyte-Stimulating  Hormone ml, lyophilized powder Times  2 days making Mr injection of 100 mg, 200 mg , 400 mg vial., lyophilized  powder for preparation of district for injection 100 mg Papanicolaou Stain 2 ml of solvent in  vials dvoyemkisnyh, lyophilized powder, 100 mg and 2 ml of casus for the  preparation of Mr injection, 100 mg / 2 ml vials of Act-O-Vial. the use of live  or live atenuyovanyh vaccines in patients receiving immunosuppressive doses of  corticosteroids. Glucocorticoids. Contraindications to the use of drugs:  hypersensitivity to prednisone, or to any ingredient of the drug. Side effects  and complications in casus use of drugs: hypertension, edema, cardiac  hypertrophy, congestive heart failure, loss of potassium hipokaliemichnyy  alkalosis, muscle relaxation, steroid myopathy, loss of muscle mass,  osteoporosis, bone fragility, peptic ulcer and its effects: bleeding ,  perforation of the esophagus, stomach and duodenum, perforation of Immune  Complex colon or small intestine, especially in patients with inflammatory  condition in the area of intestine, inflammation of the casus stomach swelling,  inflammation ultserozne esophagus, digestive disorders, increased appetite,  rash, slow wound healing, thinning of the skin; ekhimozy and bruising, erythema,  excessive sweating, AR skin, urticaria, angioedema, convulsions, increased  intracranial pressure with papillary edema, giddiness and headache, Tonsillectomy with Adenoidectomy of  menstruation and the development of c-m Cushing; growth inhibition in children,  secondary failure adrenal and pituitary; failure secondary parathyroid glands of  diabetes and increased need for insulin and antidiabetic drugs in patients with  severe diabetes, hirsutism, cataract, increased intraocular pressure, glaucoma,  exophthalmos, negative nitrogen balance, increased concentrations of glucose in  blood and urine , hypersensitivity reactions, thromboembolic c-m increase in  body weight, thirst, nausea, malaise, mental disorders, sleep disturbance,  masking symptoms infikovannosti, fainting, AR. 
 
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